A new study on steelhead trout in Oregon offers genetic evidence that wild and hatchery fish are different at the DNA level, and that they can become different with surprising speed. The research, recently published in Nature Communications, found that after one generation of hatchery culture, the offspring of wild fish and first-generation hatchery fish differed in the activity of more than 700 genes. A single generation of adaptation to the hatchery resulted in observable changes at the DNA level that were passed on to offspring, scientists reported. This research was conducted at Oregon State University in collaboration with the Oregon Department of Fisheries and Wildlife. Scientists say the findings essentially close the case on whether or not wild and hatchery fish can be genetically different.